Can not derive ought from *is.
Can derive ought not from *is.
Any/all false "ought..." relates to "belief".
Any/all true "ought not..." relates to "knowledge".
All "ought" exists in all-belief-based ignorance (according to belief in false *is).
All "ought not" exists in all-knowing (according to acknowledgement of true *is).
Problem reduces into knowing any/all *not to* believe viz. approaches all-knowing.
"I ought not to (any longer) believe..." negates any/all belief-based suffering/death.