As the great Richard Feynman pointed out, all we know is what is wrong. Like many scientists, he took Popper seriously. We know, for instance, that the biblical account of creation is wrong. Even if god did create the universe, he didn't do it in the way Genesis suggests. There was no global flood, although the ubiquity of such stories suggests that there were ancestral stories that related to the end of the last ice age, when the straits of Gibraltar and the Bosporus were breached and the Mediterranean and Black Sea resulted, a process that might well have taken 40 days. There is no archaeological evidence of Exodus, etc, etc.
we may be wrong but is it possible to improve our efforts to impartially experience reality so we can profit by admitting we are wrong? I had just linked to C I R E T which is dedicated to a more meaningful and complete quality of reason. For those open to think out of the box, it opens new doors. Of course being open is a great threat to our ego and habits that have already decided right and wrong so only a few are willing to think out of the box.