I've read all of it, and that's a lot of reading (years of accumulated full comic-pages, still publishing 3 times a week). It's brilliant. A simple word: brilliant.
Wikipedia describes it vastly better than I can:
Any woman of intellect just have to love it, okay, I'm no woman of intellect but seriously, it's indescribably different a feel you get from the webcomic than you'll get anywhere else reading. It's simply about persons, natural geniuses (not taught), being called "Sparks", controlling an alternate-history Europe and in a clash of interests with each other, some being smarter than others, all of them dangerous individuals, this woman no less although she's kind-of the angle of them all. Lots of interesting characters, many non-human (bringing in the fantasy-style), including Frankensteinian monsters, talking circus-cats (later turned general of an army of "jägers", a kind-of war-loving humanoid monster), precious soulful dancing porcelain mechanical robot-women which just I've never encountered their likes in any other fictional world, and much much more!Girl Genius has the tagline of "Adventure, Romance, MAD SCIENCE!". It features a female lead character in an alternate-history Victorian-style "steampunk" setting, although elements veer from what is usually thought of as steampunk. Kaja Foglio, one of the co-creators, describes it as "gaslamp fantasy" instead to suggest its more fantastic style.
Hope you like it I'm addicted like hell, love all the characters, and especially the world they've been put in, a really rich and unique world in its own ways.
It's a must read, but take your time, it will take days to read, and that's after you've gotten hooked.
While this isn't straight-forward philosophy, you can't help but see all the ideas and stuff going on in the series, sometimes taking philosophical turns, but mostly the "mad science" turn. Gender roles come forth and are broken like nowhere else, a woman is the sole to-become mistress able to seize control over a world full of self-interest individuals.